Effects of Prune Supplementation on Cardiometabolic Health in Postmenopausal Women: An Ancillary Analysis of a 12-Month Randomized Controlled Trial, The Prune Study

JOURNAL: J Nutr. 2024 Mar 13:S0022-3166(24)00161-5

AUTHORS: Janhavi J Damani, Connie J Rogers, Hang Lee, Nicole CA Strock, Kristen J Koltun, Nancy I Williams, Connie Weaver, Mario G Ferruzzi, Cindy H Nakatsu, Mary Jane De Souza

Estrogen withdrawal during menopause is associated with an unfavorable cardiometabolic profile. Prunes (dried plums) represent an emerging functional food and have been previously demonstrated to improve bone health. However, our understanding of the effects of daily prune intake on cardiometabolic risk factors in postmenopausal women has been limited. In this ancillary of The Prune Study, conducted among 183 postmenopausal women, prune supplementation at 50 grams daily or 100 grams daily for 12 month did not improve glycemic control but researchers concluded it may prevent adverse changes in central adiposity in postmenopausal women.